Chikungunya fever is an arboviral disease transmitted to humans by the bite of infected Aedes aegypti or A. albopictus mosquitoes. Chikungunya virus was first isolated from the blood of a febrile patient in Tanzania in 1953. Outbreaks of Chikungunya fever have occurred in many areas of Africa, Asia, Europe, and the Pacific islands. In 2013, for the first time Chikungunya virus was identified in the Americas on islands in the Caribbean. Chikungunya disease rarely occurs in the United States, and reported cases are usually associated with travel to a high-risk area. Five cases of Chikungunya virus infection have been reported in travel-associated Wisconsin residents since 2006.