Monkeypox: Vaccine Information

Two vaccines are available for preventing monkeypox infection in the United States: JYNNEOS (Imvamune or Imvanex) and ACAM2000.

JYNNEOS is the preferred vaccine for the current outbreak of monkeypox. Vaccine supply for JYNNEOS is increasing in the United States but may be limited in some areas.

A masked adult with sleeve rolled up pointing to his vaccinated arm

 

In Wisconsin, JYNNEOS is currently available for the following people:

  • Known close contacts who are identified by public health, and
  • People with certain risk factors who are more likely to have been recently exposed to monkeypox, even if they have not had documented exposure to someone with confirmed monkeypox.

JYNNEOS

How much vaccine is available?

JYNNEOS is the vaccine most commonly used for preventing monkeypox infection in the United States. It is currently being distributed by the Centers for Disease Control and Prevention (CDC). To date, the national vaccine supply has been very limited. Because of this, the federal government is using case counts and proportions of the population at risk for severe disease from monkeypox to determine state allocations of JYNNEOS. This has happened in phases with criteria for eligibility for use.

Who can get the JYNNEOS vaccine?

The Department of Health Services (DHS) is currently following the CDC’s recommendation to prioritize the JYNNEOS vaccine for people at the highest risk of infection.

JYNNEOS vaccine is currently available in Wisconsin for the following people:

  • Known contacts who are identified by public health through case investigation, contact tracing, and risk exposure assessments. 

  • Presumed contacts who may meet the following criteria: 

    • People who know that a sexual partner in the past 14 days was diagnosed with monkeypox. 

    • People who attended an event or venue where there was known monkeypox exposure. 

    • Gay men, bisexual men, trans men and women, any men who have sex with men, and gender non-conforming/non-binary people, who have had multiple sexual partners in the last 14 days.

  • People considered to have an elevated risk of exposure to monkeypox in the future: 

    • Gay men, bisexual men, trans men and women, any men who have sex with men, and gender non-conforming/non-binary people who expect to have multiple or anonymous sex partners. This may include people living with HIV and people who take HIV pre-exposure because of increased risk of sexually transmitted infections.  

    • Clinical laboratory personnel who perform testing to diagnose orthopoxviruses, including those who use polymerase chain reaction (PCR) assays for diagnosis of orthopoxviruses, including Monkeypox virus. 

    • Research laboratory workers who directly handle cultures or animals contaminated or infected with orthopoxviruses that infect humans, including Monkeypox virus, replication-competent Vaccinia virus, or recombinant Vaccinia viruses derived from replication-competent Vaccinia virus strains. 

    • Laboratory staff working with lesion swabs that may contain orthopoxviruses. This includes staff that handle swabs of lesions from suspect monkeypox cases or test for things other than orthopoxviruses, including Varicella zoster virus or Herpes virus. This also includes microbiologists that do standard bacterial cultures from these lesion swabs.

    • Certain health care providers working in sexual health clinics or other specialty settings directly caring for patients with sexually transmitted infections. 

Where can I get vaccinated?

If you are eligible for the monkeypox vaccine, DHS encourages you to contact your local or tribal health department (LTHD). DHS continues to work directly with LTHDs to supply vaccine for people who had a known exposure to someone with monkeypox and Wisconsinites who meet the eligibility criteria.

 

The JYNNEOS vaccine is also available by appointment at designated health care locations for eligible people. Please see below for a list of vaccinators accepting appointments from the public. If you meet the current eligibility requirements for vaccination and are unable to make an appointment at one of these locations, contact your LTHD for assistance connecting with a vaccinator.

Location Website/Contact Information 

Ashland County Health Department

https://co.ashland.wi.us/health_human_services
Bayfield County Health Department https://www.bayfieldcounty.wi.gov/
Brown County Public Health https://www.browncountywi.gov/departments/public-health/general-informat...
Calumet County Public Health https://www.co.calumet.wi.us/156/Public-Health
Chippewa County Department of Public Health https://www.co.chippewa.wi.us/government/public-health/
City of Appleton Health Department https://www.appleton.org/residents/health
City of Milwaukee Health Department - Menomonee Valley Site (drive-thru) https://city.milwaukee.gov/Health/
City of Racine Public Health Department https://www.cityofracine.org/health/
Columbia County Division of Public Health https://www.co.columbia.wi.us/columbiacounty/hhs/HealthHumanService/Publ...
Cudahy Health Department https://www.cudahy-wi.gov/departments/health/index.php
De Pere Health Department https://www.deperewi.gov/department/?structureid=12
Dodge County Public Health https://www.co.dodge.wi.gov/departments/departments-e-m/human-services-h...
Door County Public Health https://www.co.door.wi.gov/167/Public-Health
Eau Claire City - County Health Department https://www.eauclairewi.gov/government/our-divisions/health-department
Fond du Lac County Health Department https://www.fdlco.wi.gov/departments/departments-f-m/health-department/m...
Froedtert Memoral Hospital https://www.froedtert.com/
Froedtert (Pleasant Valley) West Bend Hospital https://www.froedtert.com/locations/health-center/pleasant-valley-health...
Froedtert/Medical College of Wisconsin Inclusion Clinic https://www.froedtert.com/locations/clinic/inclusion-health-clinic-sarge...
Grant County Health Department http://www.co.grant.wi.gov/localgov_departments_details.asp?deptid=414&l...
Green County Health Department https://www.greencountywi.org/192/Public-Health
Gundersen Health - La Crosse Clinic https://www.gundersenhealth.org/locations/la-crosse-campus/clinic/
Health Connections, Inc. www.healthconnectmke.org
Ho Chunk Nation Black River Falls https://ho-chunknation.com/
Holton Street Clinic http://www.holtonstreetclinic.org/
Iowa County Health Department https://www.iowacounty.org/Monkeypox
Jackson County Public Health https://www.co.jackson.mi.us/276/Health-Department
Jefferson County Health Department https://www.jeffersoncountywi.gov/departments/health/index.php
Kenosha County Division of Health https://www.kenoshacounty.org/297/Health-Services
La Crosse County Health Department  https://www.lacrossecounty.org/health/
Lafayette County Health Department https://www.lafayettecountywi.org/healthdepartment
Lincoln County Health Department https://co.lincoln.wi.us/health
Manitowoc County Health Department  https://manitowoccountywi.gov/departments/health-department/
Marathon County Health Department https://www.co.marathon.wi.us/Departments/HealthDepartment.aspx
Marshfield Clinic Health Center For scheduling appointments: 1-800-549-3174, option 1
Marshfield Medical Center - Minocqua For scheduling appointments: 1-800-549-3174, option 1
Marshfield Medical Center - Rice Lake Medical Offices For scheduling appointments: 1-800-549-3174, option 1
Marshfield Medical Center - Weston Medical Offices For scheduling appointments: 1-800-549-3174, option 1
Mayo Health System - Luther Campus https://www.mayoclinichealthsystem.org/locations/eau-claire
Milwaukee Health Services - MLK Clinic https://mhsi.org/
Monroe County Health Department https://www.co.monroe.wi.us/departments/health-department
North Shore Health Department https://www.nshealthdept.org/
Oneida County Health Department  https://publichealth.co.oneida.wi.us/monkeypox/
Outagamie County Public Health https://www.outagamie.org/government/f-through-m/health-human-services/p...
Outreach Community Health Center https://www.ochc-milw.org/
Pierce County Public Health https://www.co.pierce.wi.us/departments/public_health/index.php
Portage County Public Health https://www.co.portage.wi.us/department/health-and-human-services/divisi...
Public Health Madison Dane County - E Washington Ave and Park St. https://www.publichealthmdc.com/
Racine County Public Health Division https://crchd.com/
Richland County Health Department https://www.co.richland.wi.us/departments/hhs/publichealth/index.shtml
Rock County Public Health Department  https://www.co.rock.wi.us/departments/public-health/communicable-disease...
Rusk County Public Health https://ruskcounty.org/publichealth
Sauk County Health Department https://www.co.sauk.wi.us/publichealth
Sheboygan County Public Health https://www.sheboygancounty.com/departments/departments-f-q/health-and-h...
South Milwaukee/St. Francis Health Department  https://www.southmilwaukee.gov/449/Monkeypox
UW Health - West Towne Clinic 608-720-3355
Vilas County Health Department  https://www.vilascountywi.gov/departments/services/public_health_departm...
Vivent Health - Green Bay https://viventhealth.org/locations/green-bay/
Vivent Health - Kenosha https://viventhealth.org/locations/kenosha/
Vivent Health - Madison https://viventhealth.org/locations/madison/
Vivent Health - Milwaukee  https://viventhealth.org/locations/milwaukee/
Watertown Department of Public Health https://www.ci.watertown.wi.us/departments/health_department/index.php
Washburn County Health Department https://www.co.washburn.wi.us/departments/health-human-services/public-h...
Washington-Ozaukee Health Department https://www.washozwi.gov/
Waukesha County Public Health https://www.waukeshacounty.gov/publichealth
Waupaca County Public Health https://www.waupacacounty-wi.gov/departments/health_and_human_services/h...
West Allis Health Department https://www.westalliswi.gov/1941/Health-Department
Winnebago County Health Department www.winnebagopublichealth.org
Wood County Health Department https://www.co.wood.wi.us/departments/health/

*DHS will continue to keep this list updated. If you are a JYNNEOS provider and would like to be added or would like changes to be made, please email DHSMonkeypoxVaccine@dhs.wisconsin.gov

DHS encourages individuals to wait patiently, take precautions to prevent disease, and continue to check their eligibility status. Due to an extremely limited vaccine supply, vaccine is being prioritized for those most at risk for severe disease. People who are known contacts of someone with monkeypox or who have another high-risk exposure remain the highest priority. Vaccine is also being prioritized for people with HIV or other conditions that contribute to a weakened immune system.

If you do not have access to a health care provider, 211 Wisconsin can provide free, confidential support finding one near you. If you do not have access to a health care provider, dial 211 or 877-947-2211, or text your ZIP code to 898-211. Find additional resources online at 211Wisconsin.org.

How is it administered?

The JYNNEOS vaccine is a two-dose vaccine series. The two doses are administered four weeks apart for maximum effectiveness. Someone who receives the JYNNEOS vaccine is considered fully vaccinated two weeks after receiving their second dose.

  • People 18 years and older can receive JYNNEOS as either an injection between the skin (intradermally) or beneath the skin (subcutaneously).
  • People under the age of 18 can receive JYNNEOS only as an injection beneath the skin (subcutaneously).

The JYNNEOS vaccine does not cause smallpox, monkeypox, or any other disease. Even after getting vaccinated, it is important to continue to take steps to protect yourself from getting sick with monkeypox. Avoid close, skin-to-skin contact, including intimate contact, with someone who has monkeypox.


Frequently asked questions

Can JYNNEOS be given after someone is exposed to monkeypox?

Yes. To help prevent the onset of disease, JYNNEOS should be administered within four days from the date of exposure to the monkeypox virus. If the vaccine is administered between four to 14 days after the date of exposure, getting vaccinated may help reduce the severity of symptoms associated with monkeypox infection.

Who should not be given the JYNNEOS vaccine?

People should speak with a health care provider to discuss if the JYNNEOS vaccine is safe for them if they have had:

  • An allergic reaction to a previous dose of JYNNOES, OR
  • An allergic reaction to an ingredient (gentamicin, ciprofloxacin, egg protein, benzonase).

People should also talk to a health care provider about getting vaccinated if they have any of the following conditions:

  • Severe, life-threatening allergies.
  • Are pregnant, think they can be pregnant, or breastfeeding.
  • Have a weakened immune system.

How is JYNNEOS administered?

The JYNNEOS vaccine is a two-dose vaccine series. The two doses are administered four weeks apart for maximum effectiveness. Someone who receives the JYNNEOS vaccine is considered fully vaccinated two weeks after receiving their second dose.

  • People 18 years and older can receive JYNNEOS as either an injection between the skin (intradermally) or beneath the skin (subcutaneously).
  • People under the age of 18 can receive JYNNEOS only as an injection beneath the skin (subcutaneously).

The JYNNEOS vaccine does not cause smallpox, monkeypox, or any other disease. Even after getting vaccinated, it is important to continue to take steps to protect yourself from getting sick with monkeypox. Avoid close, skin-to-skin contact, including intimate contact, with someone who has monkeypox.

 

Can I be charged an administration fee for JYNNEOS if I have insurance?

Providers cannot charge a patient a fee for the vaccine itself.  However, providers may charge the patient an administration fee or seek appropriate reimbursement from the program or plan that covers administration fee for the monkeypox vaccine, such as private insurance or Medicare/Medicaid reimbursement.  Providers must administer JYNNEOS at no cost to the recipient regardless of  the vaccine recipient’s ability to pay administration fees. 

Is it safe to get the JYNNEOS vaccine if you are pregnant, think you can be pregnant, or breastfeeding?

It is unknown if pregnant people are more susceptible to monkeypox infection or more severe disease during pregnancy. However, the monkeypox virus can be transmitted to the unborn baby and to the newborn through close contact during and after birth.

The JYNNEOS vaccine should be offered to people who are pregnant or breastfeeding if they are exposed to monkeypox. People who are pregnant or breastfeeding are encouraged to talk with a health care provider about the risks and benefits of getting vaccinated.

What are the side effects?

Most people who receive the JYNNEOS vaccine will have only minor reactions like pain, redness, swelling, and itching at the injection site. In rare circumstances, people may experience muscle pain, headache, tiredness, nausea, chills, and fever.

What should I do if I have a severe allergic reaction after getting vaccinated?

Call 911 immediately or go to the nearest hospital if you have signs of an allergic reaction. Signs of an allergic reaction may include:

  • Hives
  • Swelling of the face or throat
  • Difficulty breathing
  • Increased heartbeat
  • Dizziness

Any adverse reaction after getting vaccinated should be reported to the Vaccine Adverse Event Reporting System (VAERS). In most cases, a health care provider will report the incident to VAERS. However, you can choose to report the incident yourself by visiting the VAERS website or calling 800-822-7967.

VAERS staff do not provide medical advice and can only assist with reporting adverse reactions.


ACAM2000

ACAM2000 is also authorized by the U.S Food and Drug Administration to prevent monkeypox infection. DHS will not be using the ACAM2000 vaccine. ACAM2000 carries a greater risk of certain serious side effects than JYNNEOS. ACAM2000 should not be given to:

  • People with weakened immune systems,
  • People with certain skin conditions such as eczema,
  • People heart disease, or
  • People who are pregnant, think they are pregnant, or breastfeeding.

Questions about monkeypox? Contact us! Phone: 608-267-9003 | Fax: 608-261-497

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Last Revised: September 26, 2022