Clinical Laboratory Improvement Amendments (CLIA): Application/Certification and Fee Payment
Background check applications for all users
To prepare for the transition to the new DHS DQA Provider Portal, the Division of Quality Assurance (DQA) will not accept any new background check applications for entity operators, non-client residents, or other required individuals for new or renewing entity license/certification applications, or for rehabilitation review applicants as of November 22, 2025.
DQA will resume accepting background check applications on December 15, 2025, through the DHS DQA Provider Portal. To prepare for this transition and for more information, visit our webpage. Caregiver background checks completed by entities for employees and contractors are not affected by this transition.
Select a link to learn more.
Application/certification
- How to Apply for a CLIA Certificate - Learn from Centers for Medicare & Medicaid Services (CMS) about the CLIA application process.
- CLIA Lab Changes Notification Summary (PDF) - A guide for when and how to provide notification about CLIA laboratory changes.
Fee payment
Pay CLIA Fees Online - Use the U.S. Department of the Treasury secure site to make fee payments from a bank account (ACH), debit or credit card.